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                        AI-Edigene? KRAS p.A146T Reference Standard Plus
                        KRAS A146T is an exon four mutation that does not lie within any known functional domains of the Kras protein (UniProt.org). A146T decreases Kras GTPase activity, increases phosphorylation of Mek and Erk, and is transforming in cell culture and xenografts (PMID: 19075190, PMID: 20570890).

                        Model:CBP10555

                        Update time:[2021-08-10]
                        Parameter
                         CBP10555
                        Format Genomic DNA
                        Description KRAS A146T is an exon four mutation that does not lie within any known functional domains of the Kras protein (UniProt.org). A146T decreases Kras GTPase activity, increases phosphorylation of Mek and Erk, and is transforming in cell culture and xenografts (PMID: 19075190, PMID: 20570890).
                           
                        Technical Data 
                        DNA Change c.436G>A
                        AA Change p.A146T
                        Mutation type Substitution - Missense
                        Zygosity Homozygous
                        Allelic Frequency 100%
                        Transcript NM_033360.4
                        Buffer Tris-EDTA
                           
                        Product Information 
                        Intended Use Research Use Only
                        Unit Size 1ug
                        Concentration Download for COA
                        Purofication Download for COA
                        DNA electrophoresis Download for COA
                        Sanger sequencing
                        Storage -20℃
                        Expiry 36 months from the date of manufacture
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