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                        Package-Ref? Lung Cancer Reference Standard Package
                        Contains a variety of common genes, involving Mutation, Translocation, CNV, quality control products for clinical tumor-related detection.

                        Model:CBP90022

                        Update time:[2020-10-30]
                        Parameter

                         

                        Package-Ref™ Lung Cancer Reference Standard Package
                        Cat No. CBP90022
                        Format Genomic DNA
                        Description Contains 6 tubes of standard products for reference, quality control, precision, detection limit
                                   
                        Panel-Ref™ gDNA Cocktail III Reference Standard
                        Gene AA Change CDS Change Exon Cosmic ID Expected AF
                        EFGR p.E746_A750delELREA c.2235_2249del15 GGAATTAAGAGAAGC>- 19 COSM6223 5%
                        EFGR p.L858R c.2573T>G 21 COSM6224 5%
                        EGFR p.T790M c.2369C>T 20 COSM6240 5%
                        EGFR p.G719S c.2155G>A 18 COSM6252 5%
                        BRAF p.V600E c.1799T>A 15 COSM476 內源突變
                        KRAS p.G12D c.35G>A 2 COSM521 5%
                        KRAS p.Q61H c.183A>C 3 COSM554 內源突變
                        PIK3CA p.E545K c.1633G>A 10 COSM763 5%
                        PIK3CA p.H1047R c.3140A>G 20 COSM775 內源突變
                        EML4-ALK E13-A20 DNA Translocation N/A COSF408 5%
                        CCDC6-RET E1-E12 DNA Translocation N/A COSF1271 5%
                        ERBB2 CNV Amplication N/A N/A CN=6
                        MYC CNV Amplication N/A N/A CN=10
                                   
                        Panel-Ref™ gDNA Cocktail IV Reference Standard
                        Gene AA Change CDS Change Exon Cosmic ID Expected AF
                        EGFR p.G719S c.2155G>A 18 COSM6252 5%
                        BRAF p.V600K c.1798_1799GT>AA 15 COSV56057713 5%
                        PIK3CA p.H1047R c.3140A>G 20 COSM775 5%
                        KRAS p.G13D c.38G>A 2 COSM532 5%
                        NRAS p.G12D c.182A>G 3 COSM584 5%
                        BRCA2 p.I2675Dfs*6 c.8021dup 18 COSM2071519 5%
                        SLC34A2-ROS1 E4-E32 DNA Translocation N/A COSF1197 5%
                        EML4-ALK E6-A20 DNA Translocation N/A COSF408 5%
                        CCDC6-RET E1-E12 DNA Translocation N/A COSF1271 5%
                        MET Exon 14 Skippig c.3082+1G>T N/A COSM6108462 5%
                        ERBB2 CNV Amplication N/A N/A CN=6
                        MYC CNV Amplication N/A N/A CN=7
                                   
                        Panel-Ref™  gDNA Cocktail V Reference Standard
                        Gene AA Change CDS Change Exon Cosmic ID Expected AF
                        EFGR p.E746_A750delELREA c.2235_2249del15 GGAATTAAGAGAAGC>- 19 COSM6223 3%
                        EFGR p.L858R c.2573T>G 21 COSM6224 3%
                        EGFR p.T790M c.2369C>T 20 COSM6240 3%
                        EGFR p.G719S c.2155G>A 18 COSM6252 3%
                        BRAF p.V600E c.1799T>A 15 COSM476 內源突變
                        KRAS p.G12D c.35G>A 2 COSM521 3%
                        KRAS p.Q61H c.183A>C 3 COSM554 內源突變
                        PIK3CA p.E545K c.1633G>A 10 COSM763 3%
                        PIK3CA p.H1047R c.3140A>G 20 COSM775 內源突變
                        EML4-ALK E13-A20 DNA Translocation N/A COSF408 3%
                        CCDC6-RET E1-E12 DNA Translocation N/A COSF1271 3%
                        ERBB2 CNV Amplication N/A N/A CN=4
                                   
                        Panel-Ref™  gDNA Cocktail VI Reference Standard
                        Gene AA Change CDS Change Exon Cosmic ID Expected AF
                        BRAF p.V600E c.1799T>A 15 COSM476 5%
                        PIK3CA p.H1047R c.3140A>G 20 COSM775 5%
                        KRAS p.G13D c.38G>A 2 COSM532 5%
                        BRCA2 p.I2675Dfs*6 c.8021dup 18 COSM2071519 5%
                                   
                        Panel-Ref™  gDNA Cocktail Ⅶ Reference Standard
                        Gene AA Change CDS Change Exon Cosmic ID Expected AF
                        EGFR p.E746_A750del c.2236_2250del15 19 COSM6225 5%
                        EGFR p.S768I c.2303G>T 20 COSM6241 5%
                        EGFR p.L861Q c.2582T>A 21 COSM6213 5%
                        MET CNV Amplification N/A N/A CN=6
                        ERBB2 p.A775_G776insYVMA c.2324_2325ins12 20 COSM12558 5%
                        KRAS p.G12V c.35G>T 2 COSM520 5%
                        PIK3CA p.E542K c.1624G>A 10 COSM760 5%
                        KRAS p.Q61H c.183A>C 3 COSM554 5%
                        BRAF p.V600E c.1799T>A 15 COSM476 內源突變
                        PIK3CA p.H1047R c.3140A>G 20 COSM775 內源突變
                        EGFR p.G719C c.2155G>T 18 COSM6253 5%
                        CD74-ROS1 E6-E34 DNA Translocation N/A COSF1200 5%
                        NRAS p.Q61K c.181C>A 3 COSM580 5%
                        IDH1 p.R132C c.394C>T 4 COSM28747 5%
                                   
                        陰性對照
                        Mutation 0%
                        Fusion 0%
                        Expected %AF CN=2
                                   
                        Product Information 
                        Intended Use Research Use Only
                        Unit Size 1ug/vial * 6 vials
                        Concentration Download for COA
                        Purity Download for COA
                        DNA electrophoresis Download for COA
                        Storage -20°C
                        Expiry 36 months from the date of manufacture
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